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The Bioscience Resource Project provides scientific and intellectual resources for a healthy future. It publishes Independent Science News, a media service devoted to food and agriculture, and their impacts on health and the environment. It also offers resources for scientists and educators and internships and training for students. Through its innovative scientific journalism and original biosafety review articles, the project provides unique and revealing perspectives on issues that are fundamental to the survival of people and the planet. The project does not accept advertising or corporate funding and is a non-profit 501(c)3 organization. It is completely dependent on individual donations.We invite you to join the Project as a contributor or a donor.

Bioscience Resource Project News and Views

Genome Editing Pioneer Violated Biosafety Rules

Published Thursday Sept. 17th by Independent Science News: Genome Editing Pioneer Violated Biosafety Rules, written by Ed Hammond of Prickly Research.

Synopsis: Daniel Voytas is a professor at the University of Minnesota. He is also CSO of the crop biotech company Calyxt and a co-inventor of the gene editing technique TALENS. For over two years, while they developed a new proprietary method of crop genetic engineering, the Voytas lab was also flagrantly violating US biosafety rules.
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The Failure of GMO Cotton In India

Published Tuesday 8th Sept, 2020 by Independent Science News: “The Failure of GMO Cotton In India” by Prof. Andrew Paul Gutierrez, Dr. Hans R. Herren and Dr. Peter E. Kenmore

Synopsis: By nearly all measures, hybrid Bt cotton in India is a failure. Indian yields are low and less than that of many countries which shun hybrid and GMO cotton. In 2017, 31 countries were ranked above India in terms of cotton yield. Meanwhile, despite initial decreases after adoption, applied insecticide use is now above what it was when GMO Bt cotton was introduced. Combined with the high cost of Bt hybrid cotton seed it is easy to explain the extreme economic distress of Indian farmers.

Read the full article at: https://www.independentsciencenews.org/commentaries/the-failure-of-gmo-cotton-in-india/

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Engineered COVID-19-Infected Mouse Bites Researcher Amid ‘Explosion’ Of Risky Coronavirus Research

Published Thursday Aug 13th, 2020 by Independent Science News: Engineered COVID-19-Infected Mouse Bites Researcher Amid ‘Explosion’ Of Risky Coronavirus Research by Jonathan Latham, PhD.
Synopsis: A researcher working at the University of North Carolina, Chapel Hill, has been bitten by a mouse that was infected with a genetically altered, mouse-adapted, version of SARS-CoV-2. The accident highlights the dangers of coronavirus research. It also draws attention to the rapid expansion of such research in the wake of the COVID19 pandemic. Third, it brings to light attempts by universities to conceal high risk virus research from public scrutiny. These concealments, according to academics interviewed by Independent Science News, represent clear violations of science’s historic social contract with society at large. Read the full article at: https://www.independentsciencenews.org/news/engineered-covid-19-infected-mouse-bites-researcher-amid-explosion-of-risky-coronavirus-research/
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Why We Oppose Golden Rice

Published on Friday Aug 7th, 2020, in Independent Science News: Why We Oppose Golden Rice
by The Stop Golden Rice Network.
Synopsis: Small farmers and NGOs across all of Asia oppose the introduction of GMO Golden Rice. However, the media, especially in the West, has mischaracterised this opposition as being based in ignorance and/or as orchestrated by Greenpeace, an NGO with Western roots. In this article, the Stop Golden Rice Network (SGRN), which has members from every part of Asia, puts that record straight. In the hope that future media coverage will be more accurate, SGRN sets out its scientific and social justice reasons for opposing GMO Golden Rice. These range from lack of proven efficacy and negligible safety testing to the undermining of food sovereignty, democratic rights, and general nutrition.
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A proposed Origin for SARS-CoV-2 and the COVID-19 Pandemic

Published on Wed. July 15th in Independent Science News

A proposed Origin for SARS-CoV-2 and the COVID-19 Pandemic

Written by Jonathan Latham, PhD and Allison Wilson, PhD

Synopsis: SARS-CoV-2, the virus responsible for the current pandemic, is in many ways an enigma to virologists. First, the virus enters human cells using a viral spike protein that is a tremendous fit for its human receptor (a protein called ACE2). This close fit allows the virus to spread very efficiently between people but such precision cannot plausibly have arisen by chance. Thus the virus appears to have evolved in the presence of that human receptor. Furthermore, the virus has a region on its spike protein called a furin site. This furin site allows the virus to access multiple cell types, making it able to infect and spread through lungs and other tissue types. The furin site is thus key to making SARS-CoV-2 a powerful pathogen. Since none of the closest known virus relatives of SARS-CoV-2 have a furin site, where did it come from? Third, any virus that recently jumped to humans from bats (or any other species) should undergo a period of rapid adapation to its new host. This is what happened when the coronaviruses SARS and MERS jumped to humans. Yet since the pandemic began, SARS-CoV-2 mutations have arisen but the virus has hardly evolved (in an adaptive sense) at all. Current zoonotic origin theories for SARS-CoV-2 have no satisfactory explanation for any of these evolutionary puzzles. Indeed, recent studies have made natural zoonotic origin hypotheses even less viable. For example, the Chinese CDC has ruled out Wuhan’s live market as the epidemic’s origin.

In our search for the origins of the pandemic we focussed on the nearest genetic relative of SARS-CoV-2, a bat coronavirus called RaTG13. This virus was obtained during 2012 and 2013 virus collecting trips to a mine where, shortly before, six miners had developed a mystery illness while shoveling bat feces. To learn more, we arranged the translation of a neglected Chinese Master’s thesis that documented the symptoms and hospital treatment of these miners. This thesis contains many surprises. Foremost, the miners were diagnosed as having coronavirus infections, and second, their symptoms are now recognisable as those of classic COVID-19. This and other information in the thesis caused us to rethink everything we thought we knew about the origins of the pandemic. In A Proposed Origin for SARS-CoV-2 and the COVID-19 Pandemic, we set out what we call the Mojiang Miners Passaging hypothesis. The theory proposes (1) that the miners acquired a coronavirus from the bats in the mine and (2) that this bat virus evolved extensively inside their bodies to become a highly human-adapted virus. This evolution occurred during a hospitalisation period that, for some of them, lasted many months. From the thesis we also know that blood and other samples were extracted from the miners and some of these were sent to the Wuhan Institute of Virology (WIV). We suggest that these samples contained highly human-adapted viruses and were used at the WIV for research. During this research the virus escaped, initiating the 2019 COVID-19 pandemic.

As we show, the theory solves the currently mysterious evolutionary and biological features of SARS-CoV-2 as well as explaining its eventual appearance in Wuhan. It also explains subsequent attempts to obscure the deaths of the miners and the Mojiang mine origin of RATG13.

Read the full story at: https://www.independentsciencenews.org/commentaries/a-proposed-origin-for-sars-cov-2-and-the-covid-19-pandemic/

To listen to the entire paper read out, you can go to Talking Papers: https://soundcloud.com/talkingpapers/proposed-origin-for-sarscov2

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William Sanjour Hazardous Waste Papers Now Available in UCSF Industry Documents Library

You can now search the Sanjour Hazardous Waste Papers in the UCSF Industry Documents Library. The Sanjour Hazardous waste Papers are the work files of famous EPA Whistleblower William Sanjour, who them to the Bioscience Resource Project for digitization. The digitized files were then shared with the UCSF Industry Documents Library.

About UCSF Industry Documents Library: Increasingly, connections are being made between tactics taken by the tobacco industry and other corporations that influence public health, particularly on the issues of food, climate change and pharmaceuticals. The Industry Documents Library is a portal to aid investigation about cross-industry corporate practices and this portal brings together the following archives: the Truth Tobacco Industry Documents, Drug Industry Documents, Chemical Industry Documents, Food Industry Documents, and Fossil Fuel Industry Documents.

More about the papers:

In 1974 William Sanjour was appointed branch chief at the Environmental Protection Agency’s newly formed Hazardous Waste Management Division. In this position, Sanjour had two principal responsibilities: 1) to research and document the environmental and human health problems associated with unregulated dumping of industrial hazardous waste, and 2) to research better and safer methods of treating and disposing of these wastes.

Sanjour supervised the drafting of regulations required to implement the Resource Conservation and Recovery Act (RCRA) but became increasingly concerned about industry interference and pressure on the EPA. In 1978, Sanjour became a whistle-blower to call out senior EPA officials’ efforts to weaken environmental protection regulations.

For over 20 years, Sanjour investigated and reported collusion and corruption at the EPA. He wrote articles, appeared in television and film documentaries, and testified multiple times before Congress. His knowledge and experiences have been influential in the passage of State and Federal laws governing hazardous waste as well as protecting the rights of fellow civil servants to blow the whistle on corrupt activities.

This collection reflects the day-to-day evolution of important environmental regulations, viewed from inside the EPA, and shines a light on political and industry pressures on regulators, as well as the pressures brought to bear on whistle-blowers in an attempt to silence them.

The original documents were given to the Bioscience Resource Project which coordinated and funded digitization work. Digital copies were contributed to the UCSF Chemical Industry Documents Archive in 2018.

Materials in this collection include:

  • Sanjour’s memos to file
  • communications within the Hazardous Waste Division
  • memos from industrial sources and trade associations
  • communications from Congress
  • contact with citizen groups
  • Congressional hearings
  • news clippings

Special thanks to the UCSF Library Access Services staff, who provided valuable assistance in processing this collection.

Search the UCSF collection here:

https://www.industrydocuments.ucsf.edu/chemical/collections/william-sanjour-hazardous-waste-papers/

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How the Evolution of Novel COVID-19 Variants Validates the Mojiang Miners Passage theory.

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